mushroom dispensary
Pleurotus ostreatus | Hiratake | Oyster
Pleurotus ostreatus | Hiratake | Oyster
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Cholesterol Control | General Health Maintenance | Immune Support
Shop Oyster mushrooms wholesale with the Mushroom Dispensary.
Note: Can be purchased as powders or made up in blends to personal specifications, and supplied in capsules or powders upon request.
All of our mushroom specimens and extracts are lab-tested, quality-controlled, and supplied by trusted growers on farms we have personally visited.
Summary
Summary
One of the principal culinary mushrooms, Oyster or King Trumpet mushrooms can be found growing mainly on deciduous trees, particularly Beech trees. Easily farmed, and commercialised as a source of polysaccharide extracts for immune support, P. ostreatus shows promise for general health maintenance ¹,², particularly among elderly populations. Containing lovastatin in concentrations ranging from 0.7-2.8% dried weight depending on the strain, related species including Pleurotus eryngii, Pleurotus tuber-regium and Pleurotus citronopileatus show similar immune-modulating and cholesterol-lowering activity ³⁻⁷.
Recommended Medicinal Uses
Recommended Medicinal Uses
• Reducing cholesterol levels ¹¹⁻²¹
• Counter age-related reductions in levels of vitamins C and E ²²⁻²⁷
Dose
Dose
1-2g/day polysaccharide extract or 2-3g/day mycelial biomass for general health maintenance. 10-15g/day dried fruit body for cholesterol control.
Contraindications
Contraindications
Caution is advised to patients taking protease inhibitors such as ritonavir, indinavir etc., which have been shown to raise statin levels significantly through common use of the CYP3A4 enzyme system. We recommend that medical professionals prescribing P. ostreatus check contraindications with patients’ medical history and active prescriptions.
Research
Research
1. IImmunomodulatory effect of pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory tract infections. Jesenak M, Majtan J, Rennerova Z, Kyselovic J, Banovcin P, Hrubisko M. Int Immunopharmacol. 2013;15(2):395–399.
2. Anti-allergic effect of Pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory tract infections. Jesenak M, Hrubisko M, Majtan J, Rennerova Z, Banovcin P. Phytother Res. 2014;28(3):471–474.
3. Evaluation of mushroom dietary fiber (nonstarch polysaccharides) from sclerotia of Pleurotus tuber-regium (Fries) singer as a potential antitumor agent. Zhang M, Cheung PC, Zhang LJ. Agric Food Chem. 2001;49(10):5059–5062.
4. Optimization for the production of water-soluble polysaccharide from Pleurotus citrinopileatus in submerged culture and its antitumor effect. Wang JC, Hu SH, Liang ZC, Yeh CJ. Appl Microbiol Biotechnol. 2005;67(6):759–766.
5. Hypolipidemic effect of Pleurotus eryngii extract in fat-loaded mice. Mizutani T, Inatomi S, Inazu A, Kawahara E. J Nutr Sci Vitaminol. 2010;56(1):48–53.
6. Dietary effect of Pleurotus eryngii on biochemical function and histology in hypercholesterolemic rats. Alam N, Yoon KN, Lee JS, Cho HJ, Shim MJ, Lee TS. Saudi J Biol Sci. 2011;18(4):403–409.
7. Antitumor activity of a polysaccharide from Pleurotus eryngii on mice bearing renal cancer. Yang Z, Xu J, Fu Q, Fu X, Shu T, Bi Y, Song B. Carbohydr Polym. 2013;95(2):615–620.
8. Effect of mushroom Pleurotus ostreatus and isolated fungal polysaccharide on serum and liver lipids in Syrian hamsters with hyperlipoproteinemia. Bobek P, Ginter E, Kuniak L, Babala J, Jurcovicova M, Ozdín L, Cerven J. Nutrition. 1991;7(2):105–108.
9. Cholesterol-lowering effect of the mushroom Pleurotus ostreatus in hereditary hypercholesterolemic rats. Bobek P, Ginter E, Jurcovicová M, Kuniak L. Ann Nutr Metab. 1991;35(4):191–195.
10. Effect of oyster fungus (Pleurotus ostreatus) on serum and liver lipids of Syrian hamsters with a chronic alcohol intake. Bobek P, Ginter E, Jurcovicová M, Ozdín L, Mekinová D. Physiol Res. 1991;40(3):327–332.
11. Dose-dependent hypocholesterolaemic effect of oyster mushroom (Pleurotus ostreatus) in rats. Bobek P, Ozdín L, Kajaba I. Physiol Res. 1997;46(4):327–329.
12. Dose- and time-dependent hypocholesterolemic effect of oyster mushroom (Pleurotus ostreatus) in rats. Bobek P, Ozdín L, Galbavý S. Nutrition. 1998;14(3):282–286.
13. Hypocholesterolemic activity of the genus Pleurotus (Jacq.: Fr.) P. Kumm. (Agaricales s. I., Basidiomycetes). Gunde-Cimerman N, Plemenitas A. Int J Med Mushrooms. 2001;3(4).
14. Evidence for the anti-hyperlipidaemic activity of the edible fungus Pleurotus ostreatus. Opletal L, Jahodár L, Chobot V, Zdanský P, Lukes J, Brátová M, Solichová D, Blunden G, Dacke CG, Patel AV. Br J Biomed Sci. 1997;54(4):240–243.
15. Dietary mushroom (Pleurotus ostreatus) ameliorates atherogenic lipid in hypercholesterolaemic rats. Hossain S, Hashimoto M, Choudhury EK, Alam N, Hussain S, Hasan M, Choudhury SK, Mahmud I. Clin Exp Pharmacol Physiol. 2003;30(7):470–475.
16. Role of oyster mushroom (Pleurotus florida) as hypocholesterolemic/ antiatherogenic agent. Bajaj M, Vadhera S, Brar AP, Soni GL. Indian J Exp Biol. 1997;35(10):1070–1075.
17. Cholesterol-lowering effect of Pleurotus species (Agaricomycetideae) (Abstracts of papers published in 1991-1999). Int J Med Mushrooms. 1999;1(4):371–380.
18. A lectin from the edible and medicinal mushroom Pleurotus ostreatus(Jacq.: Fr.) Kumm. as a food intake suppressing substance. Kawagishi H, Yokoyama S, Nakamura H, Tokuyama S. Int J Med Mushrooms. 2001;3(2-3):168.
19. Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects. Khatun K, Mahtab H, Khanam PA, Sayeed MA, Khan KA. Mymensingh Med J. 2007;16(1):94–99.
20. Antihyperlipidemic effect of Pleurotus ostreatus in HIV: results of a pilot proof-of-principle clinical trial. Abrams DI, Couey P, Shade SB, Kelly ME, Kamanu-Elias N, Stamets PE. Int J Med Mushrooms. 2007;9(3):204.
21. Antihyperlipidemic effects of Pleurotus ostreatus (oyster mushrooms) in HIV-infected individuals taking antiretroviral therapy. Abrams DI, Couey P, Shade SB, Kelly ME, Kamanu-Elias N, Stamets P. BMC Complement Altern Med. 2011;11:60.
22. Effect of oyster mushroom (Pleurotus ostreatus) on pathological changes in dimethylhydrazine-induced rat colon cancer. Bobek P, Galbavy S, Ozdin L. Oncol Rep. 1998;5(3):727–730.
23. Cytotoxic effect of oyster mushroom Pleurotus ostreatus on human androgen-independent prostate cancer PC-3 cell. Gu YH, Sivam G. J Med Food. 2006;9(2):196–204.
24. Effects of Lentinus edodes, Grifola frondosa and Pleurotus ostreatusadministration on cancer outbreak and activities of macrophages and lymphocytes in mice treated with a carcinogen N-butyl-N-butanolnitrosamine. Kurashige S, Aleusawa Y, Endo F. Immunopharm Immunodetox. 1997;19(2):175–183.
25. Antioxidant activity of the oyster mushroom, Pleurotus ostreatus, on CCl(4)-induced liver injury in rats. Jayakumar T, Ramesh E, Geraldine P. Food Chem Toxicol. 2006;44(12):1989–1996.
26. Protective effect of an extract of the oyster mushroom, Pleurotus ostreatus, on antioxidants of major organs of aged rats. Jayakumar T, Thomas PA, Geraldine P. Exp Gerontol. 2007;42(3):183–191.
27. An extract of the oyster mushroom, Pleurotus ostreatus, increases catalase gene expression and reduces protein oxidation during aging in rats. Jayakumar T, Thomas PA, Isai M, Geraldine P. Zhong Xi Yi Jie He Xue Bao. 2010;8(8):774–780.
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