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Antrodia camphorata | Taiwanofungus camphoratus | Stout Camphor Fungus
Antrodia camphorata | Taiwanofungus camphoratus | Stout Camphor Fungus
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Liver Health | Antioxidant | Cardiovascular Support
Shop Antrodia camphorata wholesale mycelium powder with the Mushroom Dispensary.
Note: Can be purchased as powders or made up in blends to personal specifications, and supplied in capsules or powders upon request.
All of our mushroom specimens and extracts are lab-tested, quality-controlled, and supplied by trusted growers on farms we have personally visited.
Summary
Summary
This native Taiwanese mushroom has attracted interest due to its exceptionally high concentration of triterpenoid compounds and their structural diversity. Other important bioactive compounds include polysaccharides, maleic/succinic acid derivatives, benzenoids, and benzoquinone derivatives ¹⁻⁴. In the wild, the Antrodia camphorata mushroom grows solely on the stout camphor tree, or Cinnamomum kanehirai. The fruiting body only develops fully once the tree is dead. With many trees felled to supply demand for this unique and extremely lucrative mushroom, C. kanehirai is now protected by the Taiwanese government ⁵. Nowadays, commercial cultivation of A. camphorata has been developed to produce either a cultivated fruiting body, pure mycelium, or mycelial biomass. Levels of triterpenes are highest in the fruiting body products, and lowest in the mycelial biomass products, with liquid fermentation mycelial products offering a cost-effective intermediate option.
A. camphorata has traditionally been used to treat various heart conditions, including hypertension and atherosclerosis. A. camphorata extracts have been reported to inhibit the thickening of blood vessel walls and promote vasodilation ³³⁻³⁴.
Recommended Medicinal Uses
Recommended Medicinal Uses
• Hepatoprotective properties ⁵⁻⁹
• Anti-hepatitis B & C activity ¹⁶⁻¹⁸
• Suppress the invasive potential of liver cancer cells ¹⁹⁻²³
• Inhibition of cancer cell growth, migration & apoptosis in breast, prostate, liver, bladder, cervical, and oral carcinoma ¹,²⁴⁻²⁹
• Immune-modulating and anti-inflammatory ³⁰
• Inhibition in the development of airway hyperresponsiveness in asthma ³⁰
• Protecting kidneys from autoimmune disease ³¹,³²
• Treating cardiovascular diseases ³³⁻³⁴
Dose
Dose
While the more expensive fruiting body contains the highest level of triterpenes and is preferred in Taiwan for cancer treatment, mycelium produced by liquid fermentation is increasingly available and has been shown to offer a cost-effective alternative for the treatment of liver conditions, with a recommended dose of 1-3g/day.
Contraindications
Contraindications
Caution should be exercised when prescribing to patients on anti-coagulant medication. We recommend that medical professionals prescribing Antrodia camphorata check contraindications with patients’ medical history and active prescriptions.
Research
Research
1. Review of pharmacological effects of Antrodia camphorata and its bioactive compounds. Geethangili M, Tzeng YM. Evid Based Complement Alternat Med. 2011;2011:212641.
2. Analysis of Taiwan patents for the medicinal mushroom ‘Niu-Chang-Chih’. Chen YF, Lu WL, Wu MD, Yuan GF. Recent Pat Food Nutr Agric. 2013;5(1):62–69.
3. Immunomodulatory effect of polysaccharides extracted from the medicinal mushroom Antrodia camphorata (higher Basidiomycetes) in specific pathogen-free chickens. Song AR, Qin D, Zhao C, Sun XL, Huang F, Kong C, Yang S. Int J Med Mushrooms. 2014;16(1):95–103.
4. New anti-inflammatory aromatic components from Antrodia camphorata. Chen YC, Chiu HL, Chao CY, Lin WH, Chao LK, Huang GJ, Kuo YH. Int J Mol Sci. 2013;14(3):4629–4639.
5. Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases. Ao ZH, Xu ZH, Lu ZM, Xu HY, Zhang XM, Dou WF. J Ethnopharmacol. 2009;121(2):194–212.
6. Further studies on the hepatoprotective effect of Antrodia camphorata in submerged culture on ethanol-induced acute liver injury in rats. Lu ZM, Tao WY, Xu HY, Ao ZH, Zhang XM, Xu ZH. Nat Prod Res. 2011;25(7):684–695.
7. Protective effects of Antrodia cinnamomea against liver injury. Liu YW, Lu KH, Ho CT, Sheen LY. J Tradit Complement Med. 2012;2(4):284–294.
8. Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea. Yue PY, Wong YY, Wong KY, Tsoi YK, Leung KS. Chin Med. 2013;8(1):21.
9. Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. Huang GJ, Deng JS, Huang SS, Lee CY, Hou WC, Wang SY, Sung PJ, Kuo YH. Food Chem. 2013;141(3):3020–3027.
10. Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage. Huang CH, Chang YY, Liu CW, Kang WY, Lin YL, Chang HC, Chen YC. J Agric Food Chem. 2010;58(6):3859–3866.
11. Effects of Antrodia camphorata on alcohol clearance and antifibrosis in livers of rats continuously fed alcohol. Wu MT, Tzang BS, Chang YY, Chiu CH, Kang WY, Huang CH, Chen YC. J Agric Food Chem. 2011;59(8):4248–4254.
12. Further studies on the hepatoprotective effect of Antrodia camphorata in submerged culture on ethanol-induced acute liver injury in rats. Lu ZM, Tao WY, Xu HY, Ao ZH, Zhang XM, Xu ZH. Nat Prod Res. 2011;25(7):684–695.
13. Antioxidative and hepatoprotective effects of Antrodia camphorata extract. Hsiao G, Shen MY, Lin KH, Lan MH, Wu LY, Chou DS, Lin CH, Su CH, Sheu JR. J Agric Food Chem. 2003;51(11):3302–3308.
14. Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes. Hseu YC, Chang WC, Hseu YT, Lee CY, Yech YJ, Chen PC, Chen JY, Yang HL. Life Sci. 2002;71(4):469–482.
15. Antioxidant properties of Antrodia camphorata in submerged culture. Song TY, Yen GC. J Agric Food Chem. 2002;50(11):3322–3327.
16. Protective effects of a neutral polysaccharide isolated from the mycelium of Antrodia cinnamomea on Propionibacterium acnes and lipopolysaccharide induced hepatic injury in mice. Han HF, Nakamura N, Zuo F, Hirakawa A, Yokozawa T, Hattori M. Chem Pharm Bull. 2006;54(4):496–500.
17. Antrodia camporata polysaccharides exhibit anti-hepatitis B virus effects. Lee IH, Huang RL, Chen CT, Chen HC, Hsu WC, Lu MK. FEMS Microbiol Lett. 2002;209(1):63–67.
18. Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease. Phuong do T, Ma CM, Hattori M, Jin JS. Phytother Res. 2009;23(4):582–584.
19. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor κB pathway. Hsu YL, Kuo PL, Cho CY, Ni WC, Tzeng TF, Ng LT, Kuo YH, Lin CC. Food Chem Toxicol. 2007;45(7):1249–1257.
20. Induction of apoptosis in human hepatoma cells by mycelia of Antrodia camphorata in submerged culture. Song TY, Hsu SL, Yen GC. J Ethnopharmacol. 2005;100(1-2):158–167.
21. Mycelia from Antrodia camphorata in submerged culture induce apoptosis of human hepatoma HepG2 cells possibly through regulation of Fas pathway. Song TY, Hsu SL, Yeh CT, Yen GC. J Agric Food Chem. 2005;53(14):5559–5564.
22. Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway. Hsieh YC, Rao YK, Wu CC, Huang CY, Geethangili M, Hsu SL, Tzeng YM. Chem Res Toxicol. 2010;23(7):1256–1267.
23. Medicinal fungus Antrodia cinnamomea inhibits growth and cancer stem cell characteristics of hepatocellular carcinoma. Liu YM, Liu YK, Lan KL, Lee YW, Tsai TH, Chen YJ. Evid Based Complement Alternat Med. 2013;2013:569737.
24. Antrodia camphorata extract induces replicative senescence in superficial TCC, and inhibits the absolute migration capability in invasive bladder carcinoma cells. Peng CC, Chen KC, Peng RY, Chyau CC, Su CH, Hsieh-Li HM. J Ethnopharmacol. 2007;109(1):93–103.
25. Inhibition of cyclooxygenase-2 and induction of apoptosis in estrogen-nonresponsive breast cancer cells by Antrodia camphorata. Hseu YC, Chen SC, Tsai PC, Chen CS, Lu FJ, Chang NW, Yang HL. Food Chem Toxicol. 2007;45(7):1107–1115.
26. Unique Formosan mushroom Antrodia camphorata differentially inhibits androgen-responsive LNCaP and -independent PC-3 prostate cancer cell. Chen KC, Peng CC, Peng RY, Su CH, Chiang HS, Yan JH, Hsieh-Li HM. Nutr Cancer. 2007;57(1):111–121.
27. Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway. Yang HL, Kuo YH, Tsai CT, Huang YT, Chen SC, Chang HW, Lin E, Lin WH, Hseu YC. Food Chem Toxicol. 2011;49(1):290–298.
28. Cytotoxic effect and induction of apoptosis in human cervical cancer cells by Antrodia camphorata. Yang PY, Hu DN, Liu FS. Am J Chin Med. 2013;41(5):1169–1180.
29. Anticancer effects of eleven triterpenoids derived from Antrodia camphorata. Lee YP, Tsai WC, Ko CJ, Rao YK, Yang CR, Chen DR, Yang MH, Yang CC, Tzeng YM. Anticancer Res. 2012;32(7):2727–2734.
30. Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma. Liu KJ, Leu SJ, Su CH, Chiang BL, Chen YL, Lee YL. Immunology. 2010;129(3):351–362.
31. An extract of Antrodia camphorata mycelia attenuates the progression of nephritis in systemic lupus erythematosus-prone NZB/W F1 mice. Chang JM, Lee YR, Hung LM, Liu SY, Kuo MT, Wen WC, Chen P. Evid Based Complement Alternat Med. 2011;2011:465894.
32. Review of biological and pharmacological activities of the endemic Taiwanese bitter medicinal mushroom, Antrodia camphorata (M. Zang et CH. Su) Sh. H. Wu et al. (higher Basidiomycetes). Yue PY, Wong YY, Chan TY, Law CK, Tsoi YK, Leung KS. Int J Med Mushrooms. 2012;14(3):241–256.
33. A novel inhibitory effect of Antrodia camphorata extract on vascular smooth muscle cell migration and neointima formation in mice. Li YH, Chung HC, Liu SL, Chao TH, Chen JC. Int Heart J. 2009;50(2):207–220.
34. The vasorelaxation of Antrodia camphorata mycelia: involvement of endothelial Ca(2+)-NO-cGMP pathway. Wang GJ, Tseng HW, Chou CJ, Tsai TH, Chen CT, Lu MK. Life Sci. 2003;73(21):2769–2783.
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